Last Longer Kit

Contains
- Tablets: 30mg Dapoxetine (6 pieces) 
- Spray: 1 x 15% Lidocaine (50ml bottle) 

Description
The Last Longer Kit contains both Dapoxetine - marketed as Priligy - as well as the delay spray. Both help treat premature ejaculation. 

Who is it for?
It is licensed for the treatment of premature ejaculation in adult men aged 18 to 64 years.

Effectiveness
Both these products have been proven to be effective in delaying ejaculation.

Results
- Tablets: Approximately 1 hour following a dose of 30mg.
- Spray: After applying it to the penis, wait 10-15 minutes for it to become effective.

Dapoxetine

Dapoxetine is the only drug specifically formulated and licensed for PE in adult males. The unique pharmacology of dapoxetine makes it ideal for on-demand dosing, allowing great convenience and flexibility for the patient. The clinical evidence published to date indicates that dapoxetine 30 mg or 60 mg is an efficacious and tolerable treatment for lifelong and acquired PE, leading to significant improvement not only in the main disease symptom of IELT, but also in all patient-reported outcomes. Dapoxetine is clearly a promising treatment option for PE, and its use can result in greater quality of life for the patient and their sexual partner. With the recent greater emphasis on research in the field of PE, it is hoped that the evidence base for a range of treatments, both topical and oral, will grow and prove valuable for patients.  

Delay Spray (Lidocaine Spray) 

The current scientific evidence around lidocaine includes numerous studies. In one specific study, which has been designed as a randomized single-blind placebo-controlled clinical trial, the effectiveness of Lidocaine Spray in the treatment of PE has been demonstrated. It was done on 150 lifelong PE patients with normal erection. They were randomized evenly categorized into two treatment groups. Patients were evaluated with the Arabic Index of Premature Ejaculation (AIPE) scores, intravaginal ejaculatory latency times (IELTs), and frequency of sexual intercourse before and after treatments. The mean values of the AIPE scores, IELTs, and sexual intercourse frequency in the lidocaine 5% spray group were statistically significant increased than the group of placebo after treatment (P value 0.0001). The present study deduced that local use of lidocaine 5% spray on glans penis 10-20 min prior to sexual intercourse could significantly improve PE patients, with tolerated local adverse effects.

Step 1:

• Dapoxetine: Use only for premature ejaculation. Check for side effects and consult your doctor if you have health conditions.
• Lidocaine Spray: Reduces sensitivity to delay ejaculation. Check for side effects and consult your doctor if you have skin conditions or allergies.

Step 2:

• Dapoxetine: Take one tablet 1-3 hours before sex. Do not use daily.
• Lidocaine Spray: Apply 10-15 minutes before sex to allow absorption and minimize transfer to your partner.

Step 3:

• Dapoxetine: Swallow whole with water, with or without food. Do not crush or break.
• Lidocaine Spray: Ensure the penis is clean and dry. Apply a thin layer evenly, especially on the head. Use only the recommended amount.

Step 4:

• Dapoxetine: Avoid alcohol and recreational drugs. If severe side effects occur, seek medical help.
• Lidocaine Spray: Avoid oral contact until absorbed. Rinse off if itching, rash, or burning occurs and seek medical help.

Step 5:

• Dapoxetine: No daily dose; do not exceed one tablet in 24 hours.
• Lidocaine Spray: Consider rinsing off before sex to avoid transfer. Use a condom to prevent transfer and for extra protection.

What Priligy is and what it is used for

Priligy contains an active substance called ‘dapoxetine’. This belongs to a group of medicines called ‘selective serotonin reuptake inhibitors’ (SSRIs). Priligy may also be known as a ‘urological’ medicine. 

Priligy increases the time it takes to ejaculate and can improve the control over the ejaculation. This may reduce the frustration or worry about fast ejaculation. 

Priligy is used to treat premature ejaculation in adult men aged 18 to 64 years. 

Premature ejaculation is when a man ejaculates with little sexual stimulation and before the man wants. This can cause problems for the man and may cause problems in sexual relationships.

What you need to know before you take Priligy

Do not take Priligy if:

• you are allergic to dapoxetine or any of the other ingredients of this medicine (listed below)
• you have heart problems, such as heart failure or problems with the heart rhythm 
• you have a history of fainting 
• you have ever had mania (symptoms include feeling over−excited, irritable or not being able to think clearly) or severe depression 
• you have moderate or severe liver problems. 
• you are taking: 

Do not take Priligy at the same time as any of the medicines listed above. If you have taken any of these medicines, you will need to wait 14 days after you stop taking it before you can start taking Priligy. Once you have stopped taking Priligy, you will need to wait 7 days before taking any of the medicines listed above. If you are not sure about what to do, talk to your doctor or pharmacist before taking this medicine.

• Certain medicines for fungal infection, including ketoconazole and itraconazole
• Certain medicines for HIV, including ritonavir, saquinavir, nelfinavir and atazanavir
• Certain antibiotics for treating infection, including telithromycin
• Nefazodone − an antidepressant 

Tell your doctor or pharmacist if you are taking any of the following medicines:

• Medicines for mental health problems other than depression 
• Non−steroidal anti−inflammatory medicines such as ibuprofen or acetylsalicylic acid 
• Medicines to thin your blood, such as warfarin 
• Certain medicines used to treat erectile dysfunction, such as sildenafil, tadalafil or vardenafil, as these medicines may lower your blood pressure, possibly upon standing 
• Certain medicines used to treat high blood pressure and chest pain (angina) (such as verapamil and diltiazem), or enlarged prostate, as these medicines may also lower your blood pressure, possibly upon standing 
• Certain other medicines for fungal infection, such as fluconazole 
• Certain other medicines for HIV, such as amprenavir and fosamprenavir 
• Certain other antibiotics for treating infection, such as erythromycin and clarithromycin 
• Aprepitant − used to treat nausea. 

If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking this medicine. This is because Priligy can affect the way some other medicines work. Also some other medicines can affect the way Priligy works. Therefore, use of other medicines may affect the maximum dose of Priligy you’re allowed to take.

Talk to your doctor, pharmacist or nurse before taking Priligy if: 

• You have not been diagnosed with premature ejaculation 
• You also have another sexual problem, such as erectile dysfunction 
• You have a history of dizziness from low blood pressure • You use recreational drugs such as ecstasy, LSD, narcotics or benzodiazepines 
• You drink alcohol (see section “Priligy with food, drink and alcohol”) 
• You have ever had a mental health problem such as depression, mania (symptoms include feeling over−excited, irritable or not being able to think clearly), bipolar disorder (symptoms include serious mood swings between mania and depression) or schizophrenia (a psychiatric disease) 
• You have epilepsy 
• You have a history of bleeding or blood clotting problems 
• You have kidney problems 
• You have, or are at risk of, high pressure in the eye (glaucoma). 

If any of the above apply to you (or you are not sure), talk to your doctor or pharmacist before taking this medicine.

Before you start taking this medicine, your doctor should perform a test to make sure that your blood pressure doesn’t drop too much when you stand up from lying down.

Children and adolescents

This medicine should not be used in children or adolescents under age 18 years. 

Priligy with food, drink and alcohol

• Do not drink grapefruit juice within 24 hours prior to taking this medicine as this can increase the level of this medicine in your body.
• This medicine can be taken with or without food.
• You should take this medicine with at least one full glass of water.
• Avoid alcohol when taking this medicine.
• The effects of alcohol such as feeling dizzy, sleepy and having slow reactions, may be increased if taken with this medicine.
• Drinking alcohol while taking this medicine may increase your risk of injury from fainting or from other side effects.

Pregnancy, breast−feeding and fertility 

This medicine should not be taken by women. 

Driving and using machines

You may feel sleepy, dizzy, faint, have difficulty concentrating and blurred vision while taking this medicine. If you experience any of these or similar effects, you should avoid driving or operating hazardous machinery. The effects of alcohol may be increased if taken with this medicine and you may be more at risk of injury from fainting or from other side effects if you take this medicine with alcohol.

Priligy contains lactose 

This medicine contains lactose (a type of sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product. 

Priligy contains sodium 

This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium free’.

How to take Priligy

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. 

• The recommended dose is 30 mg. Your doctor may increase the dose to 60 mg. 
• Only take the medicine 1 to 3 hours before sexual activity is anticipated.
• Do not take this medicine more than once every 24 hours or every day. 
• Swallow the tablets whole to avoid a bitter taste, with at least one full glass of water. This may help lower your chance of fainting (see ‘Fainting and low blood pressure’ below)
• This medicine can be taken with or without food.
• This medicine should not be used by men under 18 or over 65 years of age.
• Discuss your Priligy treatment with your doctor after the first 4 weeks or after 6 doses to see whether you should continue treatment. If treatment is continued, you should see your doctor again to discuss this at least every six months.

If you take more Priligy than you should

Tell your doctor or pharmacist if you have taken more tablets than you should. You may feel sick or be sick.

If you stop taking Priligy

Talk to your doctor before you stop taking this medicine. You may have problems sleeping and feel dizzy after you stop taking this medicine, even if you have not taken it every day. 

If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. 

Stop taking Priligy and see your doctor straight away if:

• You have fits (seizures)
• You faint or feel light headed when you stand up
• You notice any changes in your mood
• You have any thoughts of suicide or harming yourself. 

If you notice any of the above, stop taking this medicine and see your doctor straight away.

Fainting and low blood pressure 

This medicine can make you faint or make your blood pressure drop when you stand up. To help lower the chance of this happening:

• Take this medicine with at least one full glass of water.
• Do not take this medicine if you are dehydrated (you do not have enough water in your body).

This can happen if:

- You have not had anything to drink in the past 4 to 6 hours 

- You have been sweating for a long time 

- You have an illness where you have a high temperature, diarrhea or being sick.

• If you feel like you might faint (such as feeling sick, feeling dizzy, light headed, confused, sweaty or an abnormal heart beat), or feel light headed when you stand up, immediately lie down so your head is lower than the rest of your body or sit down with your head between your knees until you feel better. This will stop you from falling and hurting yourself if you do faint.
• Do not stand up quickly after you have been sitting or lying down for a long time.
• Do not drive or use any tools or machines if you feel faint when taking this medicine.
• Tell your doctor if you faint when taking this medicine.

Very common side effects (may affect more than 1 in 10 men): 

• Feeling dizzy 
• Headache 
• Feeling sick.

Common side effects (may affect up to 1 in 10 men): 

• Feeling irritable, anxious, agitated or restless 
• Feeling numb or having ‘pins and needles’
• Difficulty getting or keeping an erection
• Sweating more than normal or flushing 
• Diarrhea, constipation or having wind
• Stomach pain, bloating or being sick
• Problems sleeping or strange dreams
• Feeling tired or sleepy, yawning
• Blocked nose (nasal congestion)
• A rise in blood pressure
• Difficulty concentrating
• Shaking or trembling
• Lower interest in sex
• Ringing in the ears
• Blurred vision
• Indigestion
• Dry mouth.

Uncommon side effects (may affect up to 1 in 100 men): 

• Fainting or feeling dizzy upon standing (see advice above)
• Change in mood, feeling overly excited or feelings of paranoia
• Feeling confused, disoriented or unable to think clearly
• Slow or irregular heartbeat or increase in heart rate
• Loss of sex drive, problems reaching orgasm
• Feeling weak, sedated, lethargic or fatigued
• Feeling depressed, nervous or indifferent
• Feeling hot, jittery, abnormal or drunk
• Vision problems, eye pain or dilated pupils
• Low or high blood pressure
• Feeling itchy or cold sweat
• Spinning sensation
• Abnormal taste
• Teeth grinding.

Rare side effects (may affect up to 1 in 1,000 men): 

• Feeling dizzy following exertion
• Sudden onset of sleep
• Urgency of bowel action.

Reporting of side effects 

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.

What Priligy contains

The active substance is dapoxetine. Each tablet contains 30 mg or 60 mg dapoxetine as a hydrochloride salt.

The other ingredients are:

• Tablet core: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate.
• Tablet coating: lactose monohydrate, hypromellose, titanium dioxide (E171), triacetin, Iron Oxide Black (E172), Iron Oxide Yellow (E172).